EVALUATION OF BLEND OF EXCIPIENTS FOR DIRECT COMPRESSION OF OXYTETRACYCLINE HYDROCHLORIDE TABLETS

Document Type : Original Article

Authors

Department of Industrial Pharmacy, Faculty of Pharmacy, Assiut University, Assiut, Egypt

Abstract

Directly compressible vehicles such as Avicel, Emdex, sugartab, Anhydrous Lactose U.S.P, and STA-Rx 1500 starch were evaluated either singly or in binary blends in the ratios of 1:1,1:3 and 3:1 w/w, to formulate oxytetracycline hydrochloride tablets. Avicel, Celutab and STA-Rx 1500 starch were found to be the most suitable single vehicles for the preparation of oxytetracycline hydrochloride tablets.