SOLUBILIZATION OF MEFENAMIC ACID BY NON-IONIC SURFACTANTS

Document Type : Original Article

Authors

1 Department of Pharmaceutics, Faculty of Pharmacy, Cairo University, Cairo, Egypt

2 Department of Pharmaceutics, Faculty of Pharmacy, El-Azhar University, Nasr City, Cairo, Egypt

Abstract

Mefenamic acid was solubilized by series of non-ionic surfactant solutions. It was found that the solubilizing capacity of the surfactant solution increased linearly by increasing the surfactant concentrations above their CMC's.
The solvent power of the different micelles was affected by change in surfactant structure.