Assiut University, Faculty of Pharmacy
Bulletin of Pharmaceutical Sciences Assiut University
1110-0052
3009-7703
13
1
1990
06
30
STUDY OF MUCILAGE AND PECTINS OF PANCRATIUM SICKENBERGERI ASCH ET. SFTH AND ALLIUM SATIVUM L.
1
8
EN
A.
A.
Ali
Department of Pharmacognosy, Faculty of Pharmacy, Assiut University, Assiut, Egypt
M.
A.
El-Shanawany
Department of Pharmacognosy, Faculty of Pharmacy, Assiut University, Assiut, Egypt
M.
A.
Ramadan
Department of Pharmacognosy, Faculty of Pharmacy, Assiut University, Assiut, Egypt
O.
M.
El-Tewasy
Department of Pharmacognosy, Faculty of Pharmacy, Assiut University, Assiut, Egypt
10.21608/bfsa.1990.70541
<em>The mucilage of Pancratium sickenbergeri consists of rhamnose (2.02%), arabinose (6.02%), mannose (26.29%) and glucose (65.65%). The pectic substance of Allium sativm L. is composed of arabinose (2.41%), mannose (17.64%), glucose (78.63%) and galacturonic acid (38.4%). These investigations were achieved by TLC, GLC and GC/MS.</em>
https://bpsa.journals.ekb.eg/article_70541.html
https://bpsa.journals.ekb.eg/article_70541_d3d67d4b07fd7b74df579edc76d39c30.pdf
Assiut University, Faculty of Pharmacy
Bulletin of Pharmaceutical Sciences Assiut University
1110-0052
3009-7703
13
1
1990
06
30
MACRO- AND MICROMORPHOLOGY OF THE STEMS AND LEAVES OF FICUS INFECTORIA (ROXB.)
9
24
EN
E.
Y.
Backheet
Department of Pharmacognosy, Faculty of Pharmacy, Assiut University, Assiut, Egypt
10.21608/bfsa.1990.70542
<em>The macro- and micromorphology of the stem and leaves of Ficus infectoria (Roxb.) are presented with the aim of finding their characters by which they could he identified and differentiated, both in the entire and powdered forms</em><em>.</em>
https://bpsa.journals.ekb.eg/article_70542.html
https://bpsa.journals.ekb.eg/article_70542_1e2f896306724e4b42c0d41df840fd6e.pdf
Assiut University, Faculty of Pharmacy
Bulletin of Pharmaceutical Sciences Assiut University
1110-0052
3009-7703
13
1
1990
06
30
MACRO- AND MICROMORPHOLOGICAL STUDY OF TRICHODESMA CALCARATUM COSS.
25
38
EN
M.
A.
Ramadan
Department of Pharmacognosy, Faculty of Pharmacy, Assiut University, Assiut, Egypt
10.21608/bfsa.1990.70543
<em>The macro- and Micromorphological characters of the leaf, stem and root of Trichodesma calcaratum Coss, growing in Egypt are presented with the aim of finding out the characteristic features by which the plant could be identified from other closely related species or varieties.</em>
https://bpsa.journals.ekb.eg/article_70543.html
https://bpsa.journals.ekb.eg/article_70543_7bfaa373c934667aae18a055e26e2689.pdf
Assiut University, Faculty of Pharmacy
Bulletin of Pharmaceutical Sciences Assiut University
1110-0052
3009-7703
13
1
1990
06
30
PHYTOCHEMICAL STUDY OF MAERUA CRASSIFOLIA FORSSK. GROWING IN EGYPT
39
49
EN
D.
W.
Bishay
Department of Pharmacognosy, Faculty of Pharmacy, Assiut University, Assiut, Egypt
M.
A.
Abdel-Baky
Department of Pharmacognosy, Faculty of Pharmacy, Assiut University, Assiut, Egypt
M.
A.
Ramadan
Department of Pharmacognosy, Faculty of Pharmacy, Assiut University, Assiut, Egypt
Z.
Z.
Ibrahim
Department of Pharmacognosy, Faculty of Pharmacy, Assiut University, Assiut, Egypt
H.
Itokawa
Tokyo College of Pharmacy, Tokyo, Japan
K.
Takeya
Tokyo College of Pharmacy, Tokyo, Japan
10.21608/bfsa.1990.70544
<em>Phytochemical study of the aerial parts of Maerua crassifolia Forssk. resulted in the isolation and identification of kaempferol, quercetin, quercetin-3-0-arabinopyranoside, kaempferol-3-0-galactorhamnoside, rutin, lyoniresinol-3-0-glucopyranoside and stachydrine. These compounds were isolated and identified from this plant for the first time. The identification was based on physical, chemical and spectral studies including UV, IR, <sup>1</sup>H-NMR ,<sup>13</sup>NMR and MS spectra.</em>
https://bpsa.journals.ekb.eg/article_70544.html
https://bpsa.journals.ekb.eg/article_70544_c3591ffc4a18fc4b0cc018e1e4e89d62.pdf
Assiut University, Faculty of Pharmacy
Bulletin of Pharmaceutical Sciences Assiut University
1110-0052
3009-7703
13
1
1990
06
30
PHYTOCHEMICAL STUDY OF EUPHORBIA HETEROPHYLLA L. CULTIVATED IN EGYPT
51
58
EN
N.
A.
El-Emary
Department of Pharmacognosy, Faculty of Pharmacy, Assiut University, Assiut, Egypt
M.
A.
Makboul
Department of Pharmacognosy, Faculty of Pharmacy, Assiut University, Assiut, Egypt
M.
A.
Abdel-Hafiz
Department of Pharmacognosy, Faculty of Pharmacy, Assiut University, Assiut, Egypt
S.
F.
Farag
Department of Pharmacognosy, Faculty of Pharmacy, Assiut University, Assiut, Egypt
10.21608/bfsa.1990.70545
<em>A phytochemical study of Euphorbia heterophylla L. cultivated in Egypt is presented. </em><em>b</em><em>-amyrin, </em><em>b</em><em>-sitosterol taraxasterol acetate, </em><em>b</em><em>-sitosterol glucoside and hydrocarbon with ketonic group were isolated from pet. ether extract of the herb. While lupeol acetate, teraxasterol, </em><em>b</em><em>-sitosterol and </em><em>b</em><em>-sitosterol glucoside were isolated from ether extract of the root. In addition quercetin 3-methyl quercetin, kaempferol-3-0-arabinoside. kaempferol-3-0-glucoside and kaempferol-7-0-glucoside sere isolated from the ethyl acetate extract of the herb. The identification of these compounds was based on physical, chemical and spectral analysis.</em>
https://bpsa.journals.ekb.eg/article_70545.html
https://bpsa.journals.ekb.eg/article_70545_00fccbec7838a5d3ff5dfc56f0beb8ca.pdf
Assiut University, Faculty of Pharmacy
Bulletin of Pharmaceutical Sciences Assiut University
1110-0052
3009-7703
13
1
1990
06
30
PHARMACOGNOSTICAL STUDY OF AVICENNIA OFFICINALIS L. GROWING IN EGYPT PART III: TERPENOIDS, FLAVONOIDS AND IRIDOIDS
59
64
EN
A.
M.
Abdel-Baky
Department of Pharmacognosy, Faculty of Pharmacy, Assiut University, Assiut, Egypt
M.
A.
Makboul
Department of Pharmacognosy, Faculty of Pharmacy, Assiut University, Assiut, Egypt
D.
W.
Bishay
Department of Pharmacognosy, Faculty of Pharmacy, Assiut University, Assiut, Egypt
S.
A.
Ross
Department of Pharmacognosy, Faculty of Pharmacy, Assiut University, Assiut, Egypt
10.21608/bfsa.1990.70546
<em>From hexane extract of Avicennia officinalis L. Lupeol, betulinic acid, ursolic acid and betulin were isolated. In addition, 4',5-dihydroxy, 3',7- dimethoxy flavone, and 8-0-acetyl harpagid iridoid were isolated from ethyl acetate extract of the plant. The identification of these compounds, was based on, physical, chemical and spectral studies including UV, IR, <sup>1</sup>H-NMR and mass analysis.</em>
https://bpsa.journals.ekb.eg/article_70546.html
https://bpsa.journals.ekb.eg/article_70546_42118c3c7aabdcd1f1cbef9eeef110b5.pdf
Assiut University, Faculty of Pharmacy
Bulletin of Pharmaceutical Sciences Assiut University
1110-0052
3009-7703
13
1
1990
06
30
PHYTOCHEMICAL STUDY OF BARLERIA CRISTATA L. AND BARLERIA PRIONITIS L. CULTIVATED IN EGYPT
65
72
EN
N.
A.
El-Emary
Department of Pharmacognosy, Faculty of Pharmacy, Assiut University, Assiut, Egypt
M.
A.
Makboul
Department of Pharmacognosy, Faculty of Pharmacy, Assiut University, Assiut, Egypt
M.
A.
Abdel-Hafiz
Department of Pharmacognosy, Faculty of Pharmacy, Assiut University, Assiut, Egypt
A.
S.
Ahmed
Department of Pharmacognosy, Faculty of Pharmacy, Assiut University, Assiut, Egypt
10.21608/bfsa.1990.70547
<em>From the hexane extract of Barleria cristata L. and Barleria prionitis L.. </em><em>a</em><em>-amyrin, </em><em>b</em><em>-Sitosterol and stigmasterol-3-0-</em><em>b</em><em>-D-glucoside were isolated. While acetyl barlerin (6,8-0-diacetyl shanzhiside methyl ester). Shanzhiside methyl ester. apigenin and apigenin-7-0-glucoside were isolated from ethyl acetate extract of B.cristata L. In addition 6,8-0-diacetyl shanzhiside methyl ester, shanzhiside methyl ester, 6-0-acetyl shanzhiside methyl ester and 8-0-acetyl shanzhiside methyl ester (barlerin), were isolated from ethyl acetate extract of B. prionitis L. The identification of these compounds was based on physical, chemical and spectral studies including IR, UV, <sup>1</sup>H and <sup>13</sup>C-NMR spectra.</em>
https://bpsa.journals.ekb.eg/article_70547.html
https://bpsa.journals.ekb.eg/article_70547_c9b112d0788ad617609ece9e8f6f99d1.pdf
Assiut University, Faculty of Pharmacy
Bulletin of Pharmaceutical Sciences Assiut University
1110-0052
3009-7703
13
1
1990
06
30
11,13-DIHYDROVERNOLIDE FROM THE FLOWER HEADS OF VERNONIA AMYGDALINA DEL.
73
76
EN
N.
A.
El-Emary
Department of Pharmacognosy, Faculty of Pharmacy, Assiut University, Assiut, Egypt
A.
A.
Attia
Department of Pharmacognosy, Faculty of Pharmacy, Assiut University, Assiut, Egypt
10.21608/bfsa.1990.70548
<em>A crystalline sesquiterpene lactone C<sub>19</sub>H<sub>24</sub>O<sub>7</sub>, mp. 187-88°C has been isolated from the flower heads of Vernonia amygdalina Del. (Asteraceae) for the first time. Intensive NMR spectral study and comparison with the data published on Vernonia lactones revealed that this compound is a lactone designated 11,13-dihydrovernolide. In addition, Vernolide, vernomygdin and vernodalin were isolated.</em>
https://bpsa.journals.ekb.eg/article_70548.html
https://bpsa.journals.ekb.eg/article_70548_dc75fd5324c287a1038a6caa8cbdb55b.pdf
Assiut University, Faculty of Pharmacy
Bulletin of Pharmaceutical Sciences Assiut University
1110-0052
3009-7703
13
1
1990
06
30
LIGNANS AND SESQUITERPENE LACTONES FROM THE ROOT BARK OF ARTEMISIA ARGENTEA L 'HER
77
81
EN
N.
A.
El-Emary
Department of Pharmacognosy, Faculty of Pharmacy, Assiut University, Assiut, Egypt
A.
A.
Attia
Department of Pharmacognosy, Faculty of Pharmacy, Assiut University, Assiut, Egypt
10.21608/bfsa.1990.70549
<em>Reinvestigation of the chemical constituents of the bark of Artemisia argentea L 'Her revealed the isolation of 5 other compounds, in addition to those reported before. Spectral analysis of the isolated compounds proved the presence of </em><em>b</em><em>-sitosterol and its glucoside, the sesquiterpene lactone [<strong>l</strong>] and the two lignans kobusin [<strong>2</strong>] and yangambin (= lirioresinol-</em><em>b</em><em>-dimethyl ether [<strong>3</strong>]. Yangambin [<strong>3</strong>] was tested in both P-388 and KB up to 100 </em><em>m</em><em>g/ml but it was inactive.</em>
https://bpsa.journals.ekb.eg/article_70549.html
https://bpsa.journals.ekb.eg/article_70549_4973b61aacece6aa742c05a3abd9b84c.pdf
Assiut University, Faculty of Pharmacy
Bulletin of Pharmaceutical Sciences Assiut University
1110-0052
3009-7703
13
1
1990
06
30
MACRO-AND MICROMORPHOLOGY OF VERBENA OFFICINALIS L. CULTIVATED IN EGYPT PART 1: THE STEM AND LEAF
83
96
EN
A.
M.
Abdel Baky
Department of Pharmacognosy, Faculty of Pharmacy, Assiut University, Assiut, Egypt
10.21608/bfsa.1990.70550
<em>The macro- and micromorphology of the stem and leaf of Verbena officinalis L. Cultivated in Egypt have been investigated in order to determine the diagnostic features by which each organ could be identified both in the entire and powdered forms.</em>
https://bpsa.journals.ekb.eg/article_70550.html
https://bpsa.journals.ekb.eg/article_70550_b3ca68ad9bb14231eb0bab097e396451.pdf
Assiut University, Faculty of Pharmacy
Bulletin of Pharmaceutical Sciences Assiut University
1110-0052
3009-7703
13
1
1990
06
30
FORMULATION OF RIFAMPICIN SUPPOSITORIES
97
102
EN
H.
Abdel-Monem
Sayed
Department of Pharmaceutics, Faculty of Pharmacy, Assiut University, Assiut, Egypt
S.
Ismail
Department of Pharmaceutics, Faculty of Pharmacy, Assiut University, Assiut, Egypt
A.
A.
Mohamed
Department of Pharmaceutics, Faculty of Pharmacy, Assiut University, Assiut, Egypt
10.21608/bfsa.1990.70551
<em>Rifampicin is a powerful bactericidal antitubercular drug. The drug was formulated as suppositories. Witepsol H<sub>12</sub> was used as the formulating base. Certain other bases as witepsol H<sub>15</sub> and W<sub>35</sub> and Massa estarinum B and BC as well as cacao butter replaced witepsol H<sub>12</sub>. Non-ionic surfactants with different chemical compositions, different HLB values as well as different physical and solubility properties were incorporated into witepsol H<sub>12</sub> at 5% concentration, of the tested surfactants were polysorbates. Spans, Myrjs and Brijs. Drug dialysis into saline solution at 37°C was studied through cellophane membrane, of the tested bases. Witepsols gave the highest dialysis rates. Polysorbates proved to be superior among the tested surfactants.</em>
https://bpsa.journals.ekb.eg/article_70551.html
https://bpsa.journals.ekb.eg/article_70551_33f4770528a66d62fd326e967a975550.pdf
Assiut University, Faculty of Pharmacy
Bulletin of Pharmaceutical Sciences Assiut University
1110-0052
3009-7703
13
1
1990
06
30
PHYTOCHEMICAL STUDY OF CROTALARIA THEBAICA (DEL.) DC. GROWING IN EGYPT
103
113
EN
D.
W.
Bishay
Department of Pharmacognosy, Faculty of Pharmacy, Assiut University, Assiut, Egypt
A.
M.
Abdel-Baky
Department of Pharmacognosy, Faculty of Pharmacy, Assiut University, Assiut, Egypt
M.
A.
Ramadan
Department of Pharmacognosy, Faculty of Pharmacy, Assiut University, Assiut, Egypt
Z.
Z.
Ibrahim
Department of Pharmacognosy, Faculty of Pharmacy, Assiut University, Assiut, Egypt
H.
Itokawa
Tokyo College of Pharmacy, Tokyo, Japan
K.
Takeya
Tokyo College of Pharmacy, Tokyo, Japan
10.21608/bfsa.1990.70552
<em>From the chloroformic extract of Crotalaria thebaica (Del.)Dc. herb, three pyrrolizidine alkaloids, Spectabiline, Monocrotaline and Crosemperine as well as </em><em>b</em><em>-sitosterol glycoside and daidzein were isolated. From the methanol extract, two saponins sere isolated and identified in the form of their methyl esters.</em>
<em>The identity of the isolated compounds was based on studies of their physical, chemical and spectral analysis including UV, IR, <sup>1</sup>H-NMR, <sup>13</sup>C-NMR and MS.</em>
https://bpsa.journals.ekb.eg/article_70552.html
https://bpsa.journals.ekb.eg/article_70552_292c00c337d6c8e1a006e9c04974aef9.pdf
Assiut University, Faculty of Pharmacy
Bulletin of Pharmaceutical Sciences Assiut University
1110-0052
3009-7703
13
1
1990
06
30
IN VITRO RELEASE OF SULCONAZOLE NITRATE FROM OINTMENT BASES
115
123
EN
S.
Ismail
Department of Pharmaceutics, Faculty of Pharmacy, Assiut University, Assiut, Egypt
A.
A.
Mohamed
Department of Pharmaceutics, Faculty of Pharmacy, Assiut University, Assiut, Egypt
M.
G.
Abd El-Mohsen
Department of Pharmaceutics, Faculty of Pharmacy, Assiut University, Assiut, Egypt
10.21608/bfsa.1990.70553
<em>The release rate of sulconazole nitrate, a new antimycotic drug, from 16 ointment formulations has been assessed. The effect of two liquid additives, viz, water and dimethyl sulfoxide (DMSO) on the release rate was investigated. The most enhancing effect was, by far, exhibited by DMSO and was found to be dependent on the additive concentration. This enhancing effect was accounted for the increase in the drug solubility in presence of DMSO rather than water. As regard to the effect of ointment base on the release pattern of the drug, water soluble bases were the superior. This observation is attributed to the fact that sulconazole nitrate is freely soluble in those water soluble bases. The difference in the release rate values exhibited when the drug was formulated in the water soluble bases is almost due to the change in formulations viscosities. It is worthy to note that the release pattern of sulconazole nitrate from all the tested ointment formulations was in agreement with the well known Higuchi diffusional model.</em>
https://bpsa.journals.ekb.eg/article_70553.html
https://bpsa.journals.ekb.eg/article_70553_3a102834c3c315a24d90d3b4c0c2614e.pdf
Assiut University, Faculty of Pharmacy
Bulletin of Pharmaceutical Sciences Assiut University
1110-0052
3009-7703
13
1
1990
06
30
BIOAVAILABILITY OF CARBACHOL CHLORIDE FROM DIFFERENT GEL FORMULATIONS
125
133
EN
S.
Ismail
Department of Pharmaceutics, Faculty of Pharmacy, Assiut University, Assiut, Egypt
A.
A.
Mohamed
Department of Pharmaceutics, Faculty of Pharmacy, Assiut University, Assiut, Egypt
M.
G.
Abd El-Mohsen
Department of Pharmaceutics, Faculty of Pharmacy, Assiut University, Assiut, Egypt
S.
A.
Hassan
Department of Ophthalmology, Faculty of Medicine, Assiut University, Assiut, Egypt
10.21608/bfsa.1990.70554
<em>The in vitro release of carbachol chloride, a cholinomimetic drug, from different ophthalmic gel-formulations has been investigated. The release data were found to be in favour of the diffusion controlled mechanism. The effect of viscosity on the release pattern has been also studied. The amount of the drug diffused from the aqueous solution of the drug was found to decrease with an increase in the solution viscosity. On the other hand, the viscosity did not affect the release rate when the drug was formulated in gels.</em>
<em>The effect of different gel formulations on the drug activity, a decrease in the intraocular pressure, IOP, was studied on human patients, It was found that the incorporation of the drug into hydrophilic gels resulted in an improvement of its activity. The parameters of drug activity: area above time curve; maximum drug response and time of maximum response. The statistical analysis of the data obtained was assessed. A correlation between the in vitro and in vivo data has been deduced.</em>
https://bpsa.journals.ekb.eg/article_70554.html
https://bpsa.journals.ekb.eg/article_70554_a0fcb44d47eefc8fb6393e64a7986892.pdf