Assiut University, Faculty of Pharmacy
Bulletin of Pharmaceutical Sciences Assiut University
1110-0052
3009-7703
6
1
1983
06
30
A COMPARATIVE MACRO AND MICROMORPHOLOGICAL STUDY OF CASSIA JAVANICA LINN. AND C. SIAMEA LAM PART I: STEMS AND LEAVES
1
18
EN
S.
M.
El-Sayyad
Department of Pharmacognosy, Faculty of Pharmacy, Assiut University, Assiut, Egypt
H.
M.
Sayed
Department of Pharmacognosy, Faculty of Pharmacy, Assiut University, Assiut, Egypt
10.21608/bfsa.1983.100710
<em>The macro and micromorphological characters of the stems and leaves of Cassia javanica Linn. and C. siamea Lam. were studied in order to identify them in both the entire and powdered forms. Moreover, a comparison between their characters established a scheme for their distinct differentiation.</em>
https://bpsa.journals.ekb.eg/article_100710.html
https://bpsa.journals.ekb.eg/article_100710_bf363be530db49c718d5cd1cece25b8d.pdf
Assiut University, Faculty of Pharmacy
Bulletin of Pharmaceutical Sciences Assiut University
1110-0052
3009-7703
6
1
1983
06
30
EFFECT OF CERTAIN ORGANIC AND INORGANIC ADDITIVES ON THE FLOCCULATION SUSPENSION CONTAINING DIFFERENT SULPHONAMIDES
19
28
EN
F.
S.
Habib
Department of Pharmaceutics, Faculty of Pharmacy, Assiut University, Assiut, Egypt
A.
E.
Aboutaleb
Department of Pharmaceutics, Faculty of Pharmacy, Assiut University, Assiut, Egypt
M.
A.
Attia
Department of Pharmaceutics, Faculty of Pharmacy, Assiut University, Assiut, Egypt
10.21608/bfsa.1983.100711
<em>The effect of various concentrations of certain organic and inorganic additives on the flocculation of suspensions containing three sulphonamides were investigated. It was found that the sedimentation volume increased relatively in the case of suspensions containing sulphadimidine, then sulphaguanidine which in turn was more than sulphanilamide. It was concluded that the nature of the additives and their concentrations as well as their effects in the cloud point of the surfactant used greatly affected the sedimentation volume. Other factors such as the difference in particle size and density among the three drugs used may also play a part.</em>
https://bpsa.journals.ekb.eg/article_100711.html
https://bpsa.journals.ekb.eg/article_100711_1de8bb3ca22f6863a7458a3cfbe6dc6e.pdf
Assiut University, Faculty of Pharmacy
Bulletin of Pharmaceutical Sciences Assiut University
1110-0052
3009-7703
6
1
1983
06
30
A PHARMACOGNOSTICAL STUDY OF IRIS GERMANICA L. VAR. ALBA PART I: A PHARMACOGNOSTICAL STUDY OF THE RHIZOME, ROOT AND LEAVES
29
46
EN
N.
A.
El-Emary
Department of Pharmacognosy, Faculty of Pharmacy, Assiut University, Assiut, Egypt
A.
M.
El-Moghazy
Department of Pharmacognosy, Faculty of Pharmacy, Assiut University, Assiut, Egypt
A.
A.
Ali
Department of Pharmacognosy, Faculty of Pharmacy, Assiut University, Assiut, Egypt
F.
M.
Darwish
Department of Pharmacognosy, Faculty of Pharmacy, Assiut University, Assiut, Egypt
10.21608/bfsa.1983.100712
<em>The Macro and micromorphological characters of each of the rhizome, root and leaf were carried out with view of finding out the diagnostic features of each for the purpose of their identification either in the entire or in the powdered form.</em>
https://bpsa.journals.ekb.eg/article_100712.html
https://bpsa.journals.ekb.eg/article_100712_1aa579b83be99bca37a679b37c2db761.pdf
Assiut University, Faculty of Pharmacy
Bulletin of Pharmaceutical Sciences Assiut University
1110-0052
3009-7703
6
1
1983
06
30
A PHARMACOGNOSTICAL STUDY OF IRIS GERMANICA L. VAR. ALBA PART II: A PHARMACOGNOSTICAL STUDY OF THE INFLORESCENCE
47
68
EN
A.
M.
El-Moghazy
Department of Pharmacognosy, Faculty of Pharmacy, Assiut University, Assiut, Egypt.
N.
A.
El-Emary
Department of Pharmacognosy, Faculty of Pharmacy, Assiut University, Assiut, Egypt.
A.
A.
Ali
Department of Pharmacognosy, Faculty of Pharmacy, Assiut University, Assiut, Egypt
F.
M.
Darwish
Department of Pharmacognosy, Faculty of Pharmacy, Assiut University, Assiut, Egypt
10.21608/bfsa.1983.100713
<em>The macro and micromorphological characters of the inflorescence was carried out with view of finding out the diagnostic features for the purpose of identification either in the entire or in the powdered form.</em>
https://bpsa.journals.ekb.eg/article_100713.html
https://bpsa.journals.ekb.eg/article_100713_018c81118d53d87338f35d4f86f726e9.pdf
Assiut University, Faculty of Pharmacy
Bulletin of Pharmaceutical Sciences Assiut University
1110-0052
3009-7703
6
1
1983
06
30
A STUDY ON THE SOLUBILITY AND STABILITY OF DIAZEPAM AND NITRAZEPAM IN BUFFERED MIXTURES
69
80
EN
A.
E.
Aboutaleb
Department of Industrial Pharmacy, Faculty of Pharmacy, Assiut University, Assiut, Egypt
M.
S.
Mesiha
Department of Industrial Pharmacy, Faculty of Pharmacy, Assiut University, Assiut, Egypt
A.
Abdel-Zaher
Department of Industrial Pharmacy, Faculty of Pharmacy, Assiut University, Assiut, Egypt
10.21608/bfsa.1983.100714
<em>Diazepam and Nitrazepam were solubilized by a series of commercial nonionic surfactant solutions buffered to pH 4, 6 and 7 at 35°C. These nonionic surfactants include Eumulgin C 1000 and C 1500 and Brij 35 and 58. It was found that the surfactant and the drug molecular structure as well as the pH value affect the quantity of Diazepam and Nitrazepam solubilized.</em>
<em>The stability of Diazepam and Nitrazepam were studied in the formulated mixtures at controlled pH values. It was found that the formulated mixtures showed maximum stability for Diazepam and Nitrazepam in mixtures adjusted to pH 6.</em>
https://bpsa.journals.ekb.eg/article_100714.html
https://bpsa.journals.ekb.eg/article_100714_3bb56cae5378799ede8dda7e564c3f97.pdf
Assiut University, Faculty of Pharmacy
Bulletin of Pharmaceutical Sciences Assiut University
1110-0052
3009-7703
6
1
1983
06
30
THE PROLONGED RELEASE OF SODIUM PHENOBARBITONE FROM SOLID DISPERSION SYSTEM
81
88
EN
A.
T.
Nouh
Department of Pharmaceutics, Faculty of Pharmacy, Mansoura University, Mansoura, Egypt
M.
S.
Mesiha
Department of Industrial Pharmacy, Faculty of Pharmacy, Assiut University, Assiut, Egypt
10.21608/bfsa.1983.100715
<em>Stearic acid was used for the preparation of solid dispersion systems containing sodium Phanobarbitone in ratios of 1:2,1:1, 2:1 drug: carrier respectively. The dispersion prepared by melting and sudden cooling was passed through a set of standard sieves and tested for in vitro release rate. The release was slow for large particle size fractions and for systems containing high stearic acid content.</em>
<em>A diffusional model was assessed for the drug release from the solid dispersion by a linear correlation observed between the percent release of the drug and the square root of time.</em>
https://bpsa.journals.ekb.eg/article_100715.html
https://bpsa.journals.ekb.eg/article_100715_ad2f42668e01d17c35f924202d6913c9.pdf
Assiut University, Faculty of Pharmacy
Bulletin of Pharmaceutical Sciences Assiut University
1110-0052
3009-7703
6
1
1983
06
30
A COMPARATIVE MACRO AND MICROMORPHOLOGICAL STUDY OF CASSIA JAVANICA LINN. AND C. SIAMEA LAM. PART II: THE FRUITS
89
102
EN
Hanaa
M.
Sayed
Department of Pharmacognosy, Faculty of Pharmacy, Assiut University, Assiut, Egypt
Samia
M.
El-Sayyad
Department of Pharmacognosy, Faculty of Pharmacy, Assiut University, Assiut, Egypt
10.21608/bfsa.1983.100716
<em>The macro and micromorphological characters of the fruits and their individual seeds of Cassia javanica Linn. and C. siamea Lam were studied. Thus provided a Key for their identification in both entire and powdered forms as well as, differentiation between them.</em>
https://bpsa.journals.ekb.eg/article_100716.html
https://bpsa.journals.ekb.eg/article_100716_0942d1fdf582b135e3977bbefa21e830.pdf
Assiut University, Faculty of Pharmacy
Bulletin of Pharmaceutical Sciences Assiut University
1110-0052
3009-7703
6
1
1983
06
30
EVALUATION OF BLEND OF EXCIPIENTS FOR DIRECT COMPRESSION OF OXYTETRACYCLINE HYDROCHLORIDE TABLETS
103
122
EN
A.
E.
Aboutaleb
Department of Industrial Pharmacy, Faculty of Pharmacy, Assiut University, Assiut, Egypt
S.
A.
Tout
Department of Industrial Pharmacy, Faculty of Pharmacy, Assiut University, Assiut, Egypt
10.21608/bfsa.1983.100717
<em>Directly compressible vehicles such as Avicel, Emdex, sugartab, Anhydrous Lactose U.S.P, and STA-Rx 1500 starch were evaluated either singly or in binary blends in the ratios of 1:1,1:3 and 3:1 w/w, to formulate oxytetracycline hydrochloride tablets. Avicel, Celutab and STA-Rx 1500 starch were found to be the most suitable single vehicles for the preparation of oxytetracycline hydrochloride tablets.</em>
https://bpsa.journals.ekb.eg/article_100717.html
https://bpsa.journals.ekb.eg/article_100717_64aa09c90aad79f686734bb7ebf5d8f7.pdf
Assiut University, Faculty of Pharmacy
Bulletin of Pharmaceutical Sciences Assiut University
1110-0052
3009-7703
6
1
1983
06
30
A STUDY ON THE DISSOLUTION OF DIRECTLY COMPRESSED DIIODOQUIN TABLETS
123
134
EN
A.
E.
Aboutaleb
Department of Industrial Pharmacy, Faculty of Pharmacy, Assiut University, Assiut, Egypt
S.
A.
Tout
Department of Industrial Pharmacy, Faculty of Pharmacy, Assiut University, Assiut, Egypt
10.21608/bfsa.1983.100950
<em>The effect of certain directly compressible vehicles on the dissolution rate of directly compressed diiodoquin tablets was investigated. Different tablet formulations containing various vehicles were selected for this study.</em>
<em>Tablets investigated were prepared using different proportions of either single or binary blends of vehicles and was found to possess different disintegration times. A significant correlation was obtained between the dissolution time (T<sub>50</sub>) and the disintegration time.</em>
<em>The dissolution rate was dependent on the type of vehicle used and its actual concentration in the formula. Other factors such as the type and concentration of the lubricant (S), hardness values of the tablets prepared, solubility of the drug as well as interactions between the drug and vehicles used may also, play a part.</em>
https://bpsa.journals.ekb.eg/article_100950.html
https://bpsa.journals.ekb.eg/article_100950_5238c7fd58b43b03d667333fc6d955f5.pdf
Assiut University, Faculty of Pharmacy
Bulletin of Pharmaceutical Sciences Assiut University
1110-0052
3009-7703
6
1
1983
06
30
EFFECT OF BINARY BLEND OF VEHICLES ON THE PHYSICAL PROPERTIES OF DIRECTLY COMPRESSED DIIODOQUIN TABLETS
135
153
EN
A.
E.
Ahoutaleb
Department of Industrial Pharmacy, Faculty of Pharmacy, Assiut University, Assiut, Egypt
S.
A.
Tout
Department of Industrial Pharmacy, Faculty of Pharmacy, Assiut University, Assiut, Egypt
10.21608/bfsa.1983.100951
<em>Directly compressible vehicles such as Avicel, Emdex, Sugratab, Anhydrous Lactose U.S.P, STA-R 1500 starch and Fmcompress, were used either singly or in binary blends in the ratios of 1:1, 1:3 and 3:1 w/w for the preparation diiodoquin tablets.</em>
<em>Avicel, Celutab and STA-Rx 1500 starch were found to be the most suitable single vehicles for the formulation of diiodoquin tablets. Tablets produced using STA-R and its blends with the other vehicles, disintegrated within the specified time. The best blends used for the manufacturing of directly compressed diiodoquin tablets were those containing avicel/STA-Rx 1500 starch 3:1 and 1:3. The least actual concentration of the vehicle needed for the preparation of good diiodoquin tablets was not less than 42.0% w/w.</em>
https://bpsa.journals.ekb.eg/article_100951.html
https://bpsa.journals.ekb.eg/article_100951_98b76541aedb531c21a96de3b0deeb74.pdf
Assiut University, Faculty of Pharmacy
Bulletin of Pharmaceutical Sciences Assiut University
1110-0052
3009-7703
6
1
1983
06
30
A COMPARATIVE MACRO-AND MICROMORPHOLOGICAL STUDY OF THE STEMS AND LEAVES OF CERTAIN JASMINUM SPECIES CULTIVATED IN EGYPT
154
171
EN
S.
M.
El-Sayyad
Department of Pharmacognosy, Faculty of Pharmacy, Assiut University, Assiut, Egypt
S.
A.
Ross
Department of Pharmacognosy, Faculty of Pharmacy, Assiut University, Assiut, Egypt
N.
A.
El-Keltawi
Department of Horticulture, Faculty of Agriculture, Assiut University, Assiut, Egypt
10.21608/bfsa.1983.100952
<em>The macro and micromorphologyical characters of the stems and leaves of Jasminum azoricum L., J. sambac Ait. C.V. double flower and J. sambac Ait. C.V. single flower were investigated in order to identify them both in entire and powdered forms as well as to differentiate between them.</em>
https://bpsa.journals.ekb.eg/article_100952.html
https://bpsa.journals.ekb.eg/article_100952_c434e1c8cf8a585f8f1d256611971e55.pdf
Assiut University, Faculty of Pharmacy
Bulletin of Pharmaceutical Sciences Assiut University
1110-0052
3009-7703
6
1
1983
06
30
A PHARMACOGNOSTICAL STUDY OF CLERODENDRON INERME L.
172
195
EN
S.
M. I.
Moustafa
Department of Pharmacognosy, Faculty of Pharmacy, Tanta University, Tanta, Egypt
I.
M.
El-Shamy
Department of Pharmacognosy, Faculty of Pharmacy, Tanta University, Tanta, Egypt
M.
M.
El-Olemy
Department of Pharmacognosy, Faculty of Pharmacy, Tanta University, Tanta, Egypt
10.21608/bfsa.1983.100953
<em>The macro and micromorphologyical characters of the flowering tops of Clerodendron inerms L. were studied with the aim to identify the organs both in the entire and powdered forms.</em>
https://bpsa.journals.ekb.eg/article_100953.html
https://bpsa.journals.ekb.eg/article_100953_c5522723efabdb305033943439ccd669.pdf
Assiut University, Faculty of Pharmacy
Bulletin of Pharmaceutical Sciences Assiut University
1110-0052
3009-7703
6
1
1983
06
30
ALKALOIDS OF HYOSCYAMUS MUTICUS TISSUE CULTURES
196
211
EN
M.
M.
El-Olemy
Department of Pharmacognosy, Faculty of Pharmacy, Tanta University, Tanta, Egypt
S.
M. I.
Moustafa
Department of Pharmacognosy, Faculty of Pharmacy, Tanta University, Tanta, Egypt
10.21608/bfsa.1983.100954
<em>Callus cultures were developed from Hyoscyamus muticus seeds and stem or Leaf midrib. The culture grows and maintains well in a number of culture media. Alkaloids were produced in all cultures. Chromatographic investigation of the alkaloid composition revealed the presence of hyoscyamine and scopolamine, together with an unidentified alkaloid. Quantitative estimation of the total alkaloids was done by the acid-dye complex spectrophotometric technique.</em>
https://bpsa.journals.ekb.eg/article_100954.html
https://bpsa.journals.ekb.eg/article_100954_e5c3048bf662974a705c7a9e9b270db3.pdf
Assiut University, Faculty of Pharmacy
Bulletin of Pharmaceutical Sciences Assiut University
1110-0052
3009-7703
6
1
1983
06
30
25S - RUSCOGENIN AND DIOSGENIN FROM THE LEAVES OF SANSEVIERIA CYLINDRICA, BOJER
212
225
EN
M.
M.
El-Olemy
Department of Pharmacognosy, Faculty of Pharmacy, Tanta University, Tanta, Egypt
H.
A.
Kadry
Department of Pharmacognosy, Faculty of Pharmacy, Tanta University, Tanta, Egypt
S.
M. I.
Moustafa
Department of Pharmacognosy, Faculty of Pharmacy, Tanta University, Tanta, Egypt
M.
M.
Bishr
Department of Pharmacognosy, Faculty of Pharmacy, Tanta University, Tanta, Egypt
10.21608/bfsa.1983.100955
<em>Chromatographic investigation of the aglycones and sapogenins of the hydroysed powder of Sansevieria cylindrica leaves revealed the presence of 13 components, three of them were chromatographically identical to </em><em>b</em><em>-sitosterol, diosgenin and ruscogenin in various TLC systems. Preparative TLC and column chromatographic techniques were used for the isolation of the three oomponents. Their identity was confirmed by TLC, gas chromatography, IR, UV, NMR and mass spectral data. The compound corresponding to ruscogenin was stereochemically confirmed as 25S-ruscogenin by IR and NMR data.</em>
https://bpsa.journals.ekb.eg/article_100955.html
https://bpsa.journals.ekb.eg/article_100955_1343038efeb85bdfc7b5c26ad31525c9.pdf
Assiut University, Faculty of Pharmacy
Bulletin of Pharmaceutical Sciences Assiut University
1110-0052
3009-7703
6
1
1983
06
30
SPECTROPHOTOMETRIC DETERMINATION OF PIPERIDINE, PIPERAZINE AND PHENMETRAZINE
226
242
EN
S.
R.
El-Shabouri
Department of Pharmaceutical Chemistry, Faculty of Pharmacy, Assiut University, Assiut, Egypt
M.
M.
Amer
Department of Pharmaceutical Chemistry, Faculty of Pharmacy, Assiut University, Assiut, Egypt
A.
M.
Taha
Department of Pharmaceutical Chemistry, Faculty of Pharmacy, Assiut University, Assiut, Egypt
P.
Y.
Khashaba
Department of Pharmaceutical Chemistry, Faculty of Pharmacy, Assiut University, Assiut, Egypt
10.21608/bfsa.1983.100956
<em>A spectrophotometric assay procedure was developed for the quantitative assay of piperazine and phenmetrazine. The method is based on the formation of enamines of these drugs by interaction with acetaldehyde. The resulting enamines interact with chloranil to form the corresponding blue aminovinylquinone which can be quantitated spectrophotometrically at </em><em>l</em><em>max 320 nm for both drugs and at </em><em>l</em><em>max '667 nm and 67C nm for piperazine and phenmetrazine respectively. The Beer-Lambert law adhered to over the 0.5-20 ug/ml range for both drugs at both </em><em>l</em><em>max. The optimum reaction conditions and the effect of variables have been studied. The method has been applied successfully to the analysis of commercially available piperazine tablets, ampoules and effervescent granules.</em>
https://bpsa.journals.ekb.eg/article_100956.html
https://bpsa.journals.ekb.eg/article_100956_e9cfbcb77c2574befb030f51ae8ff2a7.pdf