2024-03-29T16:42:58Z
https://bpsa.journals.ekb.eg/?_action=export&rf=summon&issue=15861
Bulletin of Pharmaceutical Sciences Assiut University
1110-0052
1110-0052
1981
4
1
MACRO AND MICROMORPHOLOGY OF JASMINIUM MESNYI H. CULTIVATED IN EGYPT. PART I: THE ROOT AND STEM.
A.
El-Moghazy
A.
Ali
S.
Ross
A.
Mohamed
The macro and micromorphology of roots and stems of Jasminium mesnyi H. cultivated in Egypt are given with a view of determining the diagnostic features by which both organs can be identified in the entire and powdered forms.
1981
12
31
1
14
https://bpsa.journals.ekb.eg/article_104585_e4e9841d1ed7306c76a9f449d1500cb5.pdf
Bulletin of Pharmaceutical Sciences Assiut University
1110-0052
1110-0052
1981
4
1
MACRO AND MICROMORPHOLOGY OF JASMINIUM MESNYI H. CULTIVATED IN EGYPT. PART II: THE LEAF AND FLOWER
A.
El-Moghazy
A.
Ali
S.
Ross
A.
Mohamed
The macro and micromorphology of leaf and flower of Jasminium mesnyi H. cultivated in Egypt are dealt with and illustrated for the purpose of their identification either in the entire or in the powdered form.
1981
12
31
15
31
https://bpsa.journals.ekb.eg/article_104586_6b30b744a35d4cdfc0548767185c1e4d.pdf
Bulletin of Pharmaceutical Sciences Assiut University
1110-0052
1110-0052
1981
4
1
PHARMACOGNOSTICAL STUDY OF DURANTA PLUMIERI JACQ. GROWN IN EGYPT. PART I: MORPHOLOGY AND HISTOLOGY OF THE LEAVES AND STEMS.
A.
Ali
A.
Abdel-Baky
M.
Makboul
The Morphological, Histological characters of the Leaf and stem of Duranta plumieri Jacq. growing in Egypt are presented to show the diagnostic characters of these organs by which each of them can be identified both in the entire and powdered forms.
1981
12
31
32
45
https://bpsa.journals.ekb.eg/article_104587_1eaf051b5f3279b71f5f677f845bafb4.pdf
Bulletin of Pharmaceutical Sciences Assiut University
1110-0052
1110-0052
1981
4
1
ANTIBACTERIAL ACTIVITY OF EXTRACTS, FLAVONOIDS AND ESSENTIAL OIL OF PULICARIA UNDULATA L.
D.
Bishay
S.
Abmed
C.
Gomaa
M.
Assaf
Different successive extracts prepared from the herb of Pulicaria undulata L. as well as flavonoid aglycones and essential oil were investigated for their antibacterial activity. Ether and ethyl alcohol extracts exhibited sign if cannot activity against both Staph. aureus and B cereus. The four flavonoid aglycones tested showed variable significant effects against both Staph aureus and B. cereus. The lowest minimum inhibitory concentrations (MICs) on both organisms (22.4 and 1.8 mg/ml respectively were met with aglycone A3 (Rhamnetin).
The essential oil revealed more antibacterial activity against the tested organisms than benzyl penicillin and streptomycin sulphate.
1981
12
31
46
55
https://bpsa.journals.ekb.eg/article_104588_67944b0cae95493469e6d113bb81923f.pdf
Bulletin of Pharmaceutical Sciences Assiut University
1110-0052
1110-0052
1981
4
1
POTENTIOMETRIC DETERMINATION OF THE AUTOPROTOLYSIS CONSTANT OF N-BUTANOL
Nawal
El-Rabbat
The autoprotolysis constant of n-butanol is determined at 25° potentiometrically with the aid of the two cells:
Glass electrode / HCl(m), BuOHD // ZnCl2 (sat.), BuOH, Hg2Cl2, Hg
and
Glass electrode / KOH(m), BuOH // ZnCl2 (sat. ), BuOH, Hg2Cl2, Hg
The mean activity coefficients (g±) of hydrogen chloride in n-butanol are compared to the corresponding theoretical values.
1981
12
31
56
68
https://bpsa.journals.ekb.eg/article_104589_96a5ee41daafa8c6227cf42d4387508f.pdf
Bulletin of Pharmaceutical Sciences Assiut University
1110-0052
1110-0052
1981
4
1
COLORIMETRIC ASSAY OF HEXAMETHYLENETETRAMINE
Aly
Taha
Nawal
El-Rabbat
Fardous
Abdel-Fattah
Two photometric procedures are described for the determination of hexamethylenetetramine, free and in pharmaceutical preparation. The two methods are based on color formation by the ammonia released after the hydrolysis of hexamethylenetetramine. In the first method sodium-l,2 naphthoquinone-4-sulphonate reagent was added to the hydrolyzed hexamine sample, after adjustment of the pH of the solution to 9.3, when excess of reagent was eliminated, pink color appeared that was measured at 495 nm (e= 8.6 x l03).
Ninhydrin was applied, in the second proposed method, to the hydrolyzed sample of hexamethylenetetramine after adjustment of the solution pH to 6.5. The color produced had its maximum absorbance at 565 nm with high intensity (e= 1.2 x l04).
Beer's law was obeyed in the range of concentration of 2-20 mcg of hexamine per ml with standard deviation of ± 0.66 and 2-30 mcg/ml with SD± 0.85 in the case of the first and the second methods respectively. The two methods were applied successfully to the analysis of commercially available hexamethylenetetramine tablets.
1981
12
31
69
81
https://bpsa.journals.ekb.eg/article_104590_d614120fe0549e199238d88fc74b6ac6.pdf
Bulletin of Pharmaceutical Sciences Assiut University
1110-0052
1110-0052
1981
4
1
RELEASE AND RHEOLOGICAL CHARACTERISTICS OF CHLORTETRACYCLINE HYDROCHLORIDE OPHTHALMIC OINTMENTS
H.
El-Sourady
M.
Attia
S.
El-Shanawany
The release of chlortetracycline from absorption and emulsion ointment bases were studied. The drug release rates from the emulsion bases were found to be Higher than that from the absorption bases. The presence of sod. metabisulphite and EDTA in the ointment systems under test was found to increase the release rate of the drug. Inclusion of a buffer in the aqueous phase of the emulsion systems was found to retard the release of the drug.
The rheological data reveals that there is a correlation between the breakdown of the system and the release of the drug from the system accompanying the addition of sod. Metabisulphite EDTA mixture and buffer solution to the ointment bases.
1981
12
31
82
98
https://bpsa.journals.ekb.eg/article_104591_3014f89ad9b6530acc8be8879daf17ec.pdf
Bulletin of Pharmaceutical Sciences Assiut University
1110-0052
1110-0052
1981
4
1
AN INVESTIGATION ON THE DISSOLUTION OF NITROFURANTOIN
H.
El-Sourady
A.
Sina
S.
Ibrahim
K.
Khaled
The problem of the existence of interlot and inter-tablet variation in the dissolution rates of nitrofurantion (NFT) marketed tablets, attracts, the attention for investigating the microcrystalline NFT powder used in formu1ating the marketed tablet products. The x-ray diffractometry and the differential, scanning colorimetry of five microcrystalline NFT powders obtained from different manufacturers revealed that this drug is not exhibiting polymorphism. NFT hydrates of large particle size were observed to be formed when the drug was to be in contact with water with the pH values in the acidic range. The unexpected dissolution - PH profile of stored NFT suspensions prepared by precipitation at pH 5.4 from alkaline solution may be illustrated by the possibility of tautomeric transformations in the drug. This was more revealed by the observed reversible shift of the l maxima on changing the pH of its solutions.
1981
12
31
99
119
https://bpsa.journals.ekb.eg/article_104592_df40d12e305d51b3cc80709a9af5e7cb.pdf
Bulletin of Pharmaceutical Sciences Assiut University
1110-0052
1110-0052
1981
4
1
APPLICATION OF DIALYSIS UNDER PRESSURE FOR INVESTIGATING THE INTERACTION BETWEEN CHLORAMPHENICOL AND NON-IONIC SURFACTANTS
A.
Aboutaleb
A.
Abdelzaher
Ultrafiltration technique was applied for investigating undersaturated systems containing chloramphenicol using Diaflo membrane UM 05. This drug was solubilized by a series of non-ionic surfactants which include Tween 20, Tween 40, Tween 60, Tween 80, Emulgin C1000, Emulgin C1500, Myrj 52, Myrj 53 and Myrj 59, at two different temperatures.
It was found that the amount of chloramphenicol bound to the micelles as calculated from the ultrafiltration experiments was greater for Emulgin C1000, than Emulgin C1500 on the other hand the binding capacity of the different Tweens for chloramphenicol can be arranged as follows: Tween 80 > Tween 40 > Tween 60 > Tween 20. For Myrj series, Myrj 52 was found to be greater than Myrj 53 and both were higher than Myrj 59.
1981
12
31
120
132
https://bpsa.journals.ekb.eg/article_104593_e9899a6a06c95109d41b22207bc9dcf4.pdf
Bulletin of Pharmaceutical Sciences Assiut University
1110-0052
1110-0052
1981
4
1
THE USE OF MOLECULAR SIEVE TECHNIQUE FOR STUDYING UNDERSATURATED SYSTEMS CONTAINING CHLORAMPHENICOL
A.
Aboutaleb
A.
Abdelzaher
Molecular sieve technique was carried out using sephadex G 25 fine for investigating the under-saturated systems containing chloramphenicol. This drug was solubilized by a series of commerical non-ionic surfactants which include: Tween 20, Tween 40, Tween 60, Tween 80, EmulginC1000, Emulgin C1500, Myrj 52, Myrj 53 and Myrj 59. At two different temperatures 25 and 35° it was found that the amount of chloramphenicol incorporated within the micelle as calculated by the molecular sieve technique was greater for Emulgin 1000 than Emulgin 1500, on the other hand for Tween series the following sequence was obtained: Tween 80 > Tween 40 > Tween 60 > Tween 20. For Myrj series Myrj 52 was greater than Myrj 53 which in turn was higher than Myrj 59.
The results obtained by investigating the under-saturated systems using this technique agreed with those determined by solubility method and gave further support to the partition model of solubilization and prove the validity of using this technique for investigating undersaturated solubilized systems containing non-ionic surfactants.
1981
12
31
133
150
https://bpsa.journals.ekb.eg/article_104594_6578e796d9dabc7c56ff0c0135128d85.pdf
Bulletin of Pharmaceutical Sciences Assiut University
1110-0052
1110-0052
1981
4
1
COMPARISON OF TWO METHODS FOR MEASURING PYRETHROID HYDROLYZING ESTERASES: EXTRACTION SELECTIVITY AND RADIOLABELED IDENTITY
Yehia
Abdel-Aal
David
Soderlund
Two published methods are used widely for measuring pyrethxoid hydrolyzing esterases. These two methods are based on measuring either the acid production (Jao and Casida, 1974) or the residual unhydrolyzed ester (Suzuki and Miyamoto, 1978). These methods were compared using (IRS, tirans), permethrin, labeled at the carbonyl carbon of the acid moiety, and rat liver microsomes. No consistent results were obtained and the enzyme activity determined by the first method was lower than that of the second one. The selectivity of the extract-ion procedure in method I and the identity of the labeled product were examined by TLC chromatography. Chloroform extract in acid production method contained more than 30% of the total acid released, thereby, introducing a large error in quantitation. Alkalinization of the reaction mixture prior to chloroform extraction using 1 ml buffer, pH 10, changed the extraction selectivity of acid permethrin (DCVA) in favour of the aqueous phase and consequently increased the accuracy of this method. No chemical hydrolysis of (IRS, trans) permethrin could be detected under conditions of pH 10 over 60 minute period.
1981
12
31
151
162
https://bpsa.journals.ekb.eg/article_104595_b5a5ba158cf1c79d9ba1380c5da5b446.pdf