SOLUBILIZATION OF CARBAMAZEPINE USING COSOLVENTS

Document Type : Original Article

Authors

Department of Industrial Pharmacy, Faculty of Pharmacy, Assiut University, Assiut, Egypt

Abstract

Solubilization of Carbamazepine was achieved through cosolvency using binary or ternary solvent systems at 25°. It was found that the aqueous solubility of the medicament was increased. However, the extent of the solubility promoting effect was dependent on the type and the concentration of the cosolvent used.