A STUDY ON CERTAIN SOLUBILIZED SYSTEMS CONTAINING CARBAMAZEPINE

Document Type : Original Article

Authors

Department of Industrial Pharmacy, Faculty of Pharmacy, Assiut University, Assiut, Egypt

Abstract

Solubility and ultrafiltration techniques were used for studying solubilized systems containing carbamazepine. The effect of variations in the alkyl, as well as ethylene oxide chain lengths of the surfactant molecules on the degree of solubilization of this solute was investigated. The results obtained from the solubility measurements agreed well with those obtained from ultrafiltration experiments which gave further support to the partition model of solubilization.