A study was made on the disintegration time and in vivo absorption rate of sulphadimidine tablets prepared by direct compression technique using Celutab (50% w/w) as an excipient. Tablets of greatly different disintegration times were selected for this investigation. Using urinary excretion method, it was shown that there is a relationship between disintegration time and in vivo absorption of sulphadimidine tablets, in that the tablet with faster disintegration time gives a higher absorption as indicated by the excretion rate calculated from the cummulative amount of sulphadimidine excreted.
Sakr, A., Aboutaleb, A., Elsabbagh, H., & Aly, A. (1980). A STUDY ON THE RELATIONSHIP BETWEEN DISINTEGRATION OF DIRECTLY COMPRESSED SULPHADIMIDINE TABLETS AND THEIR PHYSIOLOGICAL AVAILABILITY IN MAN. Bulletin of Pharmaceutical Sciences Assiut University, 3(1), 74-86. doi: 10.21608/bfsa.1980.104713
MLA
Adel M. Sakr; Ahmed E. Aboutaleb; Hassan M. Elsabbagh; Adel M. Aly. "A STUDY ON THE RELATIONSHIP BETWEEN DISINTEGRATION OF DIRECTLY COMPRESSED SULPHADIMIDINE TABLETS AND THEIR PHYSIOLOGICAL AVAILABILITY IN MAN". Bulletin of Pharmaceutical Sciences Assiut University, 3, 1, 1980, 74-86. doi: 10.21608/bfsa.1980.104713
HARVARD
Sakr, A., Aboutaleb, A., Elsabbagh, H., Aly, A. (1980). 'A STUDY ON THE RELATIONSHIP BETWEEN DISINTEGRATION OF DIRECTLY COMPRESSED SULPHADIMIDINE TABLETS AND THEIR PHYSIOLOGICAL AVAILABILITY IN MAN', Bulletin of Pharmaceutical Sciences Assiut University, 3(1), pp. 74-86. doi: 10.21608/bfsa.1980.104713
VANCOUVER
Sakr, A., Aboutaleb, A., Elsabbagh, H., Aly, A. A STUDY ON THE RELATIONSHIP BETWEEN DISINTEGRATION OF DIRECTLY COMPRESSED SULPHADIMIDINE TABLETS AND THEIR PHYSIOLOGICAL AVAILABILITY IN MAN. Bulletin of Pharmaceutical Sciences Assiut University, 1980; 3(1): 74-86. doi: 10.21608/bfsa.1980.104713
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