Home Articles List Article Information
Bulletin of Pharmaceutical Sciences. Assiut
Journal Archive
Volume Volume 43 (2020)
Volume Volume 42 (2019)
Volume Volume 41 (2018)
Volume Volume 40 (2017)
Volume Volume 39 (2016)
Volume Volume 38 (2015)
Volume Volume 37 (2014)
Volume Volume 36 (2013)
Volume Volume 35 (2012)
Volume Volume 34 (2011)
Volume Volume 33 (2010)
Volume Volume 32 (2009)
Volume Volume 31 (2008)
Volume Volume 30 (2007)
Volume Volume 29 (2006)
Volume Volume 28 (2005)
Volume Volume 27 (2004)
Volume Volume 26 (2003)
Volume Volume 25 (2002)
Volume Volume 24 (2001)
Volume Volume 23 (2000)
Volume Volume 22 (1999)
Volume Volume 21 (1998)
Volume Volume 20 (1997)
Volume Volume 19 (1996)
Volume Volume 18 (1995)
Volume Volume 17 (1994)
Volume Volume 16 (1993)
Volume Volume 15 (1992)
Volume Volume 14 (1991)
Volume Volume 13 (1990)
Volume Volume 12 (1989)
Volume Volume 11 (1988)
Volume Volume 10 (1987)
Volume Volume 9 (1986)
Volume Volume 8 (1985)
Volume Volume 7 (1984)
Volume Volume 6 (1983)
Volume Volume 5 (1982)
Volume Volume 4 (1981)
Volume Volume 3 (1980)
Volume Volume 2 (1979)
Volume Volume 1 (1978)
Gayatri, S., Monica, V. (2020). PRELIMINARY PHYTOCHEMICAL INVESTIGATION AND IN-VITRO ANTIDIABETIC ACTIVITY OF AN AYURVEDIC FORMULATION. Bulletin of Pharmaceutical Sciences. Assiut, 43(2), 135-139. doi: 10.21608/bfsa.2020.127400
S. Gayatri; V. Angel Seslin Monica. "PRELIMINARY PHYTOCHEMICAL INVESTIGATION AND IN-VITRO ANTIDIABETIC ACTIVITY OF AN AYURVEDIC FORMULATION". Bulletin of Pharmaceutical Sciences. Assiut, 43, 2, 2020, 135-139. doi: 10.21608/bfsa.2020.127400
Gayatri, S., Monica, V. (2020). 'PRELIMINARY PHYTOCHEMICAL INVESTIGATION AND IN-VITRO ANTIDIABETIC ACTIVITY OF AN AYURVEDIC FORMULATION', Bulletin of Pharmaceutical Sciences. Assiut, 43(2), pp. 135-139. doi: 10.21608/bfsa.2020.127400
Gayatri, S., Monica, V. PRELIMINARY PHYTOCHEMICAL INVESTIGATION AND IN-VITRO ANTIDIABETIC ACTIVITY OF AN AYURVEDIC FORMULATION. Bulletin of Pharmaceutical Sciences. Assiut, 2020; 43(2): 135-139. doi: 10.21608/bfsa.2020.127400

PRELIMINARY PHYTOCHEMICAL INVESTIGATION AND IN-VITRO ANTIDIABETIC ACTIVITY OF AN AYURVEDIC FORMULATION

Article 2, Volume 43, Issue 2, Summer and Autumn 2020, Page 135-139  XML PDF (419.34 K)
Document Type: Original Article
DOI: 10.21608/bfsa.2020.127400
Authors
S. Gayatri1; V. Angel Seslin Monica2
1Assistant Professor, Sri Ramachandra Faculty of Pharmacy, SRIHER (DU), Porur, Chennai-600116, Tamil Nadu, India
2Student, Sri Ramachandra Faculty of Pharmacy, SRIHER (DU), Porur, Chennai-600116, Tamil Nadu, India
Abstract
Objective: To carry out the preliminary phytochemical analysis and to perform the in-vitro anti diabetic activity for the ayurvedic poly herbal formulation.
Material and Methods: Preliminary phytochemical analysis was performed as per the standard procedures. In-vitro anti-diabetic activity was done by two methods namely alpha amylase inhibitory assay and alpha glucosidase inhibitory assay by taking acarbose as a standard drug for the ayurvedic formulation. Statistical analysis is carried out by means of graphpad prism software version 6.
Results and conclusion: Preliminary phytochemical analysis showed the presence of alkaloids, glycosides, phytosterols, phenols, flavonoids and terpenoids in the formulation. The poly herbal tablet produced 32.2% inhibition of alpha amylase activity at a concentration of 125 µg/ml and 80.8% inhibition of alpha glucosidase activity at a concentration of 62.5 µg/ml. The present study shows that the selected ayurvedic poly herbal tablets has an anti-diabetic activity comparable with that of allopathic drug - acarbose tablet.
Statistics
Article View: 61
PDF Download: 67