TOTAL FLAVONOID CONTENT, MICROSCOPIC AND MICROBIAL EVALUATION OF SYRIAN GINKGO BILOBA PRODUCTS

Document Type : Original Article

Authors

1 Department of Drug Quality Control and Pharmaceutical Chemistry, Faculty of Pharmacy, Al-Baath University, Homs, Syria

2 Department of Drug Quality Control and Pharmaceutical Chemistry (Drug synthesis), Faculty of Pharmacy, Al-Baath University, Homs, Syria

3 Department of Clinical Pharmacology, Faculty of Medicine, Al-Baath University, Homs, Syria

Abstract

Ginkgo Biloba (GB) is a widely used finished herbal product. Due to its natural source
there is no demand to evaluate its quality before marketing. Although GB products have shown
promising potential with the efficacy, many of these products remain untested. The Current
work aims to evaluate some quality parameter of GB finished products like total flavonoid
content (TFC), microscopic, Loss On Drying (LOD) and microbial tests in comparison with GB
crude plant. The TFC ranged from (22.86 to78.74 mg/g). Microscopic findings revealed the
presence of large amounts of starch grains in product A. Furthermore, most of the products
were heavily contaminated with bacteria and fungi. As bacterial colony counts ranged from
(103 to 7.5 105 CFU/g) and from (1.7 103 to 0.75 107 CFU/g) for fungal colony counts. Most
of the products exceeded the reference limits for LOD. thus may pose a threat to consumer's
health.
Bulletin of Pharmaceutical Sciences Assiut University
Volume 44, Issue 2
December 2021
Pages 313-321

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