EVALUATION OF BIOLOGICAL ACTIVITIES OF MATRICARIA PUBESCENS FROM ALGERIA

Benmoussa, Mohamed Taher; Nadji, Said; Boudjemaa, Soumaya; Bounab, Abdelhakim; Hadef, Youcef

doi:10.21608/bfsa.2022.271595

EVALUATION OF BIOLOGICAL ACTIVITIES OF MATRICARIA PUBESCENS FROM ALGERIA

Document Type : Original Article

Authors

¹ Department of pharmacy, University of Batna2

² Laboratory of Toxicology, University hospital of Batna,

³ Laboratory of Toxicology, University hospital of Batna

⁴ Laboratory of mineral chemistry, Faculty of pharmacy, University of Algiers

⁵ Laboratory of Analytical chemistry, Department of pharmacy, Faculty of Medicine, University of Annaba

10.21608/bfsa.2022.271595

Abstract

Abstract: Matricaria pubescens is a plant of the asteraceae family that grows wild in Algeria and throughout North Africa especially in the desert. It is commonly used as folk medicine to cure a variety of ailments in various preparations, aerial parts of the plant were sampled from two different sites in Algeria, the biological activities of the methanolic extracts and essential oils have been evaluated namely antioxidant, anti-inflammatory, antidiabetic, antibacterial, and antifungal activities, besides a safety bioassay , The essential oils of the plant have shown significant efficacy against the studied bacteria, and a strong antifungal activity against Candida albicans. Methanolic extracts and essential oils have shown noticeable anti-inflammatory activity. The essential oils showed good antidiabetic activity and weak antioxidant power. Meanwhile Matricaria pubecens essential oils noted significant cytolytic effect that may hamper its systemic use, it also noteworthy to mention the variability between the samples confirming the differences in the chemical patterns.

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