QUALITATIVE ANALYSIS FOR ILLICIT DRUGS AND NPS (NEW PSYCHOACTIVE SUBSTANCES) USING GC-MS

Putra, Galih Satrio; Sumari, Sumari; Sulistyowaty, Melanny Ika; Handajani, Magdalena Sri; Suhud, Farida; Kesuma, Dini; Anwari, Farida

doi:10.21608/bfsa.2024.261161.2000

QUALITATIVE ANALYSIS FOR ILLICIT DRUGS AND NPS (NEW PSYCHOACTIVE SUBSTANCES) USING GC-MS

Document Type : Original Article

Authors

¹ Department of Chemistry, Faculty of Mathematic and Natural Sciences, State University of Malang, Indonesia

² Department of Pharmaceutical Sciences, Faculty of Pharmacy, Universitas Airlangga, Surabaya, Indonesia

³ Department of Pharmaceutical Chemistry, Faculty of Pharmacy, University of Surabaya, Surabaya, Indonesia

⁴ Medical Laboratory Science, University of Anwar Medika, Sidoarjo,Indonesia

10.21608/bfsa.2024.261161.2000

Abstract

This research aims to analyze 500 samples for illicit drugs and NPS (New Psychoactive Substances) using GC-MS (Gas Chromatography Mass Spectrometry) in East Java Indonesia. Sample analysis was carried out by GC-MS with HP-5 column, injection port temperature of 250°C. Column temperature was maintained at 100°C for 2 minutes. It was then raised from10°C/minute to 280°C and maintained for 5 minutes Based on the results, it was detected 244 (48.8 %) Methamphetamine (MA); 30 (6 %) 3,4-Methylenedioxymethamphetamine (MDMA); 44 (8.8 %) 3,4-Methylenedioxyethylamphetamine (MDA); 56 (11.2 %) 3,4-Methylenedioxyethylamphetamine (MDEA); 106 (21.2 %) AB-Fubinaca; 5 (1.0 %) Tramadol; 5 (1.0 %) Ketamine; and 10 (2.0 %) Mephedrone. The identification of illicit drugs and NPS in confiscated materials was successfully achieved via GC-MS. The availability of GC-MS libraries is of great assistance in the identification of new drugs. Alternatively, the study of characteristic molecule fragments combined with the determination of their accurate masses can be a useful approach to identify unknown samples that were not previously analyzed.

Keywords

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