Phytochemical study of the roots of Sonchus oleraceus L. (Astraceae) growing in Egypt, afforded loliolide 1 for the first time from the genus Sonchus in addition to 15-O-β-glucopyranosyl- 11β,13-dihydrourospermal A 2, ursolic acid 3, lupeol 4, and β- sitosterol-3-O-β-glucopyranoside 5 for the first time from the species. The biological evaluation of the isolated compounds showed cytotoxic activity of 1 and 2 against L5187Y cell line, while compound 2 showed activity against PC33 cell line. In addition to antibacterial activity of compounds 1 and 2 against S. aureus, B. subtilis, E. Coli, and N. gonorrhoea. The structures of the isolated compounds were elucidated using 1D (1H and 13C), 2D (H-H COSY, HMQC and HMBC) NMR and MS spectroscopic data.
Elkhayat, E. (2009). CHEMICAL AND BIOLOGICAL INVESTIGATIONS OF THE ROOTS OF SONCHUS OLERACEUS L. GROWING IN EGYPT. Bulletin of Pharmaceutical Sciences Assiut University, 32(1), 189-197. doi: 10.21608/bfsa.2009.63356
MLA
Ehab Saad Elkhayat. "CHEMICAL AND BIOLOGICAL INVESTIGATIONS OF THE ROOTS OF SONCHUS OLERACEUS L. GROWING IN EGYPT". Bulletin of Pharmaceutical Sciences Assiut University, 32, 1, 2009, 189-197. doi: 10.21608/bfsa.2009.63356
HARVARD
Elkhayat, E. (2009). 'CHEMICAL AND BIOLOGICAL INVESTIGATIONS OF THE ROOTS OF SONCHUS OLERACEUS L. GROWING IN EGYPT', Bulletin of Pharmaceutical Sciences Assiut University, 32(1), pp. 189-197. doi: 10.21608/bfsa.2009.63356
VANCOUVER
Elkhayat, E. CHEMICAL AND BIOLOGICAL INVESTIGATIONS OF THE ROOTS OF SONCHUS OLERACEUS L. GROWING IN EGYPT. Bulletin of Pharmaceutical Sciences Assiut University, 2009; 32(1): 189-197. doi: 10.21608/bfsa.2009.63356
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