PHENOLICS OF CYPERUS ALOPECUROIDES ROTTB. INFLORESCENCES AND THEIR BIOLOGICAL ACTIVITIES

Document Type : Original Article

Authors

1 Department of Pharmacognosy, Faculty of Pharmacy, Assiut University, Assiut, Egypt

2 Department of Pharmacognosy, Faculty of Pharmacy, Al-Azhar University, Assiut, Egypt

3 Institute of Pharmaceutical Biology and Biotechnology, Heinrich- Heine-University, Universitätsstraße 1, 40225 Düsseldorf, Germany

4 Department of Pharmacognosy, Faculty of Pharmacy, Obafemi Awolowo University, Ile-Ife, Nigeria

Abstract

Sixteen phenolic compounds, scopoletin (1), isoliquiritigenin 4-
methyl ether (2), luteolin 5,3-dimethyl ether (3), luteolin 7,3-
dimethyl ether (4), aureusidin 4-methyl ether (5), apigenin (6),
luteolin (7), trans-ferulic acid (8), luteolin 4-O- -D-glucopyranoside
(9), luteolin 7-O- -D-glucopyranoside (10), quercetin
3-O- -D-glucopyranoside (11), apigenin 7-O-neohesperidoside
(12), kaempferol 3-O-rutinoside (13), quercetin 3-O-rutinoside
(14), kaempferol 3-O-[2-O-D-xylopyranosyl-6-O--L-rhamnopyranosyl]-
 -D-glucopyranoside (15) and kaempferol 3-O-[2-OD-
glucopyranosyl-6-O--L-rhamnopyranosyl]- -D-glucopyranoside
(16) were isolated from the methanolic extract of the
inflorescences of Cyperus alopecuroides Rottb. for the first time.
Their structures have been established on the basis of physical,
chemical and spectroscopic methods in addition to comparison
with literature data and/or authentic samples. The antioxidant and
cytotoxic activities in addition to -amylase inhibitory activity of
the isolated compounds have been studied.