The concentrated 70% ethanolic extracts of the air-dried powdered leaves and stem bark of Flacourtia cataphracta were subjected separately to solvent fractionation by partitioning using n-hexane, chloroform and ethyl acetate respectively. Each concentrated fraction was subjected to TLC followed by isolation, purification and identification of the available constituents. Fourteen compounds were isolated and identified by different spectral tools (UV, IR, 1H-NMR, 13C-NMR, MS) and comparison with corresponding literature data. -amyrin (1), -amyrin (2), and a mixture of -sitosterol and stigmasterol (3) were isolated from nhexane fraction of both leaves and stem bark. 2-Oxo-18benzolyloxy-13(16), 14-tetrahydrocleroda-3-ene (4), 3 -acetoxyD:A friedo oleanan-27,16 -lactone (5), 4,4'-dihydroxychalcone (6), apigenin (7) and kampferol (8) were isolated from chloroform fraction of the stem bark. -Sitosterol-3-O -D-glucoside (9), 5-Ocaffeoylquinic acid (10) were isolated from the ethyl acetate fraction of the leaves in addition to vanillin (11), benzoic acid (12), protocatechuic acid (13) and flacourtin (14) from the ethyl acetate fraction of the stem bark. The different leaf extracts were subjected to biological study which revealed that n-hexane, ethyl acetate and methanol fractions of Flacourtia cataphracta Roxb. are safe to be used as antidiarrheal, anti-inflammatory and antipyretic drug.
Sayed, H., Mohamed, M., Darwish, F., & Mohamed, A. (2006). PHYTOCHEMICAL AND BIOLOGICAL INVESTIGATIONS OF FLACOURTIA CATAPHRACTA ROXB. CULTIVATED IN EGYPT. Bulletin of Pharmaceutical Sciences Assiut University, 29(2), 371-387. doi: 10.21608/bfsa.2006.65215
MLA
Hanaa M. Sayed; Mahmoud H. Mohamed; Faten M. Darwish; Ahmed M. Mohamed. "PHYTOCHEMICAL AND BIOLOGICAL INVESTIGATIONS OF FLACOURTIA CATAPHRACTA ROXB. CULTIVATED IN EGYPT". Bulletin of Pharmaceutical Sciences Assiut University, 29, 2, 2006, 371-387. doi: 10.21608/bfsa.2006.65215
HARVARD
Sayed, H., Mohamed, M., Darwish, F., Mohamed, A. (2006). 'PHYTOCHEMICAL AND BIOLOGICAL INVESTIGATIONS OF FLACOURTIA CATAPHRACTA ROXB. CULTIVATED IN EGYPT', Bulletin of Pharmaceutical Sciences Assiut University, 29(2), pp. 371-387. doi: 10.21608/bfsa.2006.65215
VANCOUVER
Sayed, H., Mohamed, M., Darwish, F., Mohamed, A. PHYTOCHEMICAL AND BIOLOGICAL INVESTIGATIONS OF FLACOURTIA CATAPHRACTA ROXB. CULTIVATED IN EGYPT. Bulletin of Pharmaceutical Sciences Assiut University, 2006; 29(2): 371-387. doi: 10.21608/bfsa.2006.65215