PHENOLIC AND ALIPHATIC GLUCOSIDES FROM CRYPTOSTEGIA GRANDIFLORA AND CARDIOTONIC ACTIVITY OF CRYPTOSTIGMIN II

Document Type : Original Article

Authors

Department of Pharmacognosy, Faculty of Pharmacy, Assiut University, Assiut 71526, Egypt

Abstract

From the leaves of Cryptostegia grandiflora, two phenolic glucosides 2,4,6-
trihydroxybenzophenone 2-O- -glucopyranoside and Acanthoside B together with a
megastigmane (Icariside B1) and (Z)-3-hexenyl  -D-glucopyranoside have been isolated.
Moreover the cardiotonic activities of Cryptostegia extract and Cryptostigmin II, the major
cardenolide previously isolated from the same plant leaves were also investigated. The latter
showed similar effects to those of Digoxin