Flavonoid glycosides and hypotensive effect of Juglans nigra L. cultivated in Egypt

Document Type : Original Article

Authors

Department of Pharmacognosy, Faculty of Pharmacy, Assiut University, Assiut, Egypt

Abstract

From a methanolic ext. of the leaves of Juglans nigra L. (black walnut; Juglandaceae)​, kaempferol-​3-​O-​β-​glucoside, quercetin-​3-​O-​β-​glucoside and quercetin-​3-​Oβ-​glucuronide-​6"-​Et ester were isolated for the first time, along with stigmasterol-​3-​O-​β-​glucoside.  Most of the structures were established on the basis of UV, MS and NMR (1H, 13C-​NMR and DEPT) spectroscopic data.  Moreover, hypotensive and toxicol. studies were done.