Phytochemical and biological studies on the leaves of Tecoma mollis Humb. And Bonpl cultivated in Egypt

Document Type : Original Article

Authors

Department of Pharmacognosy, Faculty of Pharmacy, Assiut University, Assiut, Egypt

Abstract

α-​Amyrin, 3-​β-​hydroxy-​urs-​12-​ene-​28-​aldehyde, β-​sitosterol, ursolic acid lactone, ursolic acid, 2-​β,​3-​,​β,​19-​α-​trihydroxy-​urs-​12-​ene-​28-​oic acid (2-​tormentic acid)​, β-​sitosterol-​3-​O-​β-​D-​glucoside, apigenin-​7-​O-​α-​L-​rhamnoside, apigenin-​7-​O-​rutinoside, luteolin-​7-​O-​rutinoside, and apigenin-​6,​8-​di-​C-​β-​D-​glucopyranoside (vicenin 2) (11) were isolated for the first time fron an ethanolic ext. of the leaves of Tecoma mollis Humb and Bonpl. cultivated in Egypt.  Identification of these compds. has been established by phys. and spectral data (UV, IR, MS, 1H- and 13C-​NMR) as well as by comparison with authentic samples.  Moreover, the biol. screening showed that the non polar fraction of the alc. ext. (n-​hexane, chloroform)​, polar fraction (Et acetate, n-​butanol) and aq. ext. as well as ursolic acid possess significant anti-​inflammatory, analgesic and antipyretic activities.  In addn., the polar fraction and aq. ext. possess also a significant anticonvulsant activity.