Lignans and an alkaloid from Haplophyllum tuberculatum

Document Type : Original Article

Authors

1 Department of Pharmacognosy, Faculty of Pharmacy, Assiut University, Assiut, Egypt

2 Department of Pharmacognosy, Faculty of Pharmacy, Seuz Canal University, Ismaelia, Egypt

Abstract

The aerial parts of Haplophyllum tuberculatum (Forssk) A. Juss grown in Egypt yielded three lignans named as kusunokinin, chaerophyllin (I)​, justicidin A as well as an alkaloid, 7-​isopentenyloxy-​8-​fagarine which is reported here for the first time from H. tuberculatum., while compd. I is reported for the first time from the genus haplophyllum.  The structure elucidation of the isolated compds. are based on spectroscopic methods including 1D-​and 2D-​NMR spectra