SESQUITERPENE LACTONES AND FLAVONOIDS FROM INULA BRITANNICA (L.)

Document Type : Original Article

Author

Department of Pharmacognosy, Faculty of Pharmacy, Assiut University, Assiut, Egypt

Abstract

From Inula britannica (L.) five known sesquiterpene lactones were isolated and identified as 4a,5b-epoxyeupatolide (1); 4a,5b-epoxydesacetylovatifolin (2); 5a-hydroxydehydroleucodin (3); 14-hydroxy-2-oxoguaia-1-(10)-3-dien-5a,11bH-12,6a-olide (4) and 2-oxo-8a,10b-dihydroxyguai-3-en-1-a,5a,6b,11bH-12,6-olide (5) in addition to three known flavonoids viz. apigenin (6), apigenin-7-O-b-glucopyranoside (7) and quercetin, 3',4'-dimethoxy-7-O-b-glucopyranoside (8). The structures of these compounds were depicted through spectral studies. All the isolated compounds were reported for the first time from the mentioned plant.