SULFATED GLYCOSIDES. STRUCTURAL PROOF FOR SALVADOSIDE THROUGH COMPARISON WITH THAT REGIOSELECTIVELY SYNTHESIZED FROM D-GLUCOSE

Document Type : Original Article

Authors

1 Department of Pharmacognosy, Faculty of Pharmacy, Assiut University, Assiut 71526, Egypt

2 Department of Pharmaceutical Organic Chemistry, Faculty of Pharmacy, Assiut University, Assiut 71526, Egypt

3 Department of Organic Chemistry, Faculty of Science, University of Oulu, Oulu, Finland

Abstract

Salvadoside; sodium (1-O-benzyl-b-D-glucopyranoside-2-sulfate) [1], a recently isolated sulfated glycoside from the Egyptian plant Salvadora persica L. used in the treatment of gastritis in folk medicine, has been synthesized in four steps from glucose. The route adopted also allows regioselective synthesis of structural isomers of the target compound.