Porous calcium silicate (florite R) and controlled pore glass (CPG 75 & CPG 500) were investigated as carriers to formulate vitamin E in a free flowing powder form. The prepared dispersions were subjected to thermogravemetric analysis (TG), scanning electron microscopic examination, testing of flow ability, uniformity of content and in-vitro release of vitamin E. TG of vitamin E - porous silicas. dispersions indicated that vitamin E existed in both lightly and strongly bound state. The latter was directly related to the specific surface area of the carrier. Florite R was found to have a greater ability to hold vitamin E than controlled pore glass. the dispersions prepared using florite R and containing up to 40% w/w vitamin E showed good flowability, uniformity of content and almost 100% release of the loaded drug.
Habib, F., Nakai, Y., El-Sayed, A., & Ali, A. (1994). FORMULATION OF OILY DRUGS IN POWDER FORM USING POROUS SILICAS I. VITAMIN E. Bulletin of Pharmaceutical Sciences Assiut University, 17(2), 119-125. doi: 10.21608/bfsa.1994.69798
MLA
F. S. Habib; Yoshinbu Nakai; A. M. El-Sayed; A. S. Ali. "FORMULATION OF OILY DRUGS IN POWDER FORM USING POROUS SILICAS I. VITAMIN E". Bulletin of Pharmaceutical Sciences Assiut University, 17, 2, 1994, 119-125. doi: 10.21608/bfsa.1994.69798
HARVARD
Habib, F., Nakai, Y., El-Sayed, A., Ali, A. (1994). 'FORMULATION OF OILY DRUGS IN POWDER FORM USING POROUS SILICAS I. VITAMIN E', Bulletin of Pharmaceutical Sciences Assiut University, 17(2), pp. 119-125. doi: 10.21608/bfsa.1994.69798
VANCOUVER
Habib, F., Nakai, Y., El-Sayed, A., Ali, A. FORMULATION OF OILY DRUGS IN POWDER FORM USING POROUS SILICAS I. VITAMIN E. Bulletin of Pharmaceutical Sciences Assiut University, 1994; 17(2): 119-125. doi: 10.21608/bfsa.1994.69798