Several substituted N-aminomethylsuccinimides (I) and 1'-alkyl, or aralkyl Spiro [indolin-2-one-3,3'-pyrrolidine-2',5 -diones1 (III, XVI) were prepared. The pKa values and the anti-MMS activity of some selected members are reported. Compound XVI showed matching protection mode when compared with ethosuximide.
Shafik, R., Ibrahim, E., Abdel-Khalek, M., & El-Semary, M. (1993). SYNTHESIS OF NOVEL SUCCINIMIDES: SPIRO-, AND N-MANNICH BASE DERIVATIVES WITH POTENTIAL ANTICONVULSANT ACTIVITY. Bulletin of Pharmaceutical Sciences Assiut University, 16(1), 88-96. doi: 10.21608/bfsa.1993.70032
MLA
Ragab M. Shafik; El-Sebai A. Ibrahim; Magdi M. Abdel-Khalek; Mona El-Semary. "SYNTHESIS OF NOVEL SUCCINIMIDES: SPIRO-, AND N-MANNICH BASE DERIVATIVES WITH POTENTIAL ANTICONVULSANT ACTIVITY". Bulletin of Pharmaceutical Sciences Assiut University, 16, 1, 1993, 88-96. doi: 10.21608/bfsa.1993.70032
HARVARD
Shafik, R., Ibrahim, E., Abdel-Khalek, M., El-Semary, M. (1993). 'SYNTHESIS OF NOVEL SUCCINIMIDES: SPIRO-, AND N-MANNICH BASE DERIVATIVES WITH POTENTIAL ANTICONVULSANT ACTIVITY', Bulletin of Pharmaceutical Sciences Assiut University, 16(1), pp. 88-96. doi: 10.21608/bfsa.1993.70032
VANCOUVER
Shafik, R., Ibrahim, E., Abdel-Khalek, M., El-Semary, M. SYNTHESIS OF NOVEL SUCCINIMIDES: SPIRO-, AND N-MANNICH BASE DERIVATIVES WITH POTENTIAL ANTICONVULSANT ACTIVITY. Bulletin of Pharmaceutical Sciences Assiut University, 1993; 16(1): 88-96. doi: 10.21608/bfsa.1993.70032
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