PHYTOCHEMICAL STUDY OF MURRAYA EXOTICA L. (RUTACEAE) I- METHOXYLATED FLAVONOIDS OF THE LEAVES

Document Type : Original Article

Authors

1 Department of Pharmacognosy, Faculty of Pharmacy, Assiut University, Assiut, Egypt

2 Institut fur Angewandte Chemie, Friedrich-Alexander Universität, Erlangen, West Germany

Abstract

From the air-dried powdered leaves of Murraya exotica L. (Rutaceae), six methoxylated flavones were isolated and identified as: 3,5,6,7,8,3`,4`,5`,-octamethoxyflavone; 3,5,6,7,3`,4`,5`,-heptamethoxyflavone; 5,6,7,3`,4`,5`,-hexamethoxyflavone; 5,6,7,3`,4`,-pentamethoxyflavone; 3,5,7,3`,4`,5`,-hexamethoxyflavone and  3,5,7,8,3`,4`,5`,-heptamethoxyflavone.
The identification was based on physical, chemical and spectral studies including 1H-NMR, 13C-NMR and MS analysis.
The antimicrobial and cytotoxic activities of the isolated compounds were studied.