EVALUATION OF READILY COMPRESSIBLE EXCIPIENTS USING AN INSTRUMENTED SINGLE PUNCH TABLET MACHINE

Document Type : Original Article

Authors

1 Department of Industrial Pharmacy, Faculty of Pharmacy, Assiut University, Assiut, Egypt

2 Laboratoire de Pharmacotechnie, Faculte de Pharmacie, B.P.10, 67048 Strasbourg, France

Abstract

The compression characteristics of eight different readily compressible excipients were studied using an instrumented single punch tablet machine. These excipients were chosen according to their nature as follows: Lactose for tableting (Merck), Lactose DMV and EMDEX being sugar nature, Starch 1500 and Maltodextrin MD 02 being starch in nature, Avicel pH 101 and Elcema p 100 being cellulose in nature in addition to Emcompress (dicalcium phosphate dihydrate). The application of the instrumented tablet machine offered a good scientific comparison for the compression characteristics of these tablets excipients.