SYNTHESIS AND BIOLOGICAL ACTIVITY OF SOME NEW SALICYLIC ACID DERIVATIVES CONTAINING A QUINAZOLIN-4-ONE MOIETY

Document Type : Original Article

Authors

1 Department of Chemistry, Facu1ty of Science, Assiut University, Assiut, Egypt

2 Department of Microbiology, Faculty of Medicine, Assiut University, Assiut, Egypt

3 Department of Pharmacology, Faculty of Medicine, Assiut University, Assiut, Egypt

Abstract

 A new series of salicylic acid derivatives of the general formula (IV) was prepared through the interaction of substituted 2-aryl-3-(haloformylalkyl)-3,4-dihydroquinazolin-4-one (III) with salicylic acid, methyl salicylate and sodium salicylate. The biological activities of these compounds such as antibacteria1, analgesic and antipyretic were determined.
Bulletin of Pharmaceutical Sciences Assiut University
Volume 7, Issue 1
June 1984
Pages 224-236

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