The chemical stability of Heptaminol base in four different suppository bases was investigated in absence and presence of several stabilizers. The stability was found decreasing in the order of: Glycerogelatin, Cacao-Butter, Witepsol-E-75, and then Polyethylene-Glycols. Butylated hydroxyanisol (BHA) was the best stabilizer in the two fatty-based formulae, while tocopherol succinate was the worst. In the water-soluble bases, sodium thiosulphate was the best stabilizer, while the mixture of sodium formaldehyde sulfoxylate (SFS) with sodium edentate was the worst.
Kassem, A., El-Miligi, M., & Ali, S. (1984). FORMULATION AND STABILITY OF HEPTAMINOL SUPPOSITORIES PART III: Chemical Stability of Heptaminol Suppositories. Bulletin of Pharmaceutical Sciences Assiut University, 7(2), 288-294. doi: 10.21608/bfsa.1984.89702
MLA
Ali A. Kassem; Mohamed F. El-Miligi; Siham A. Ali. "FORMULATION AND STABILITY OF HEPTAMINOL SUPPOSITORIES PART III: Chemical Stability of Heptaminol Suppositories". Bulletin of Pharmaceutical Sciences Assiut University, 7, 2, 1984, 288-294. doi: 10.21608/bfsa.1984.89702
HARVARD
Kassem, A., El-Miligi, M., Ali, S. (1984). 'FORMULATION AND STABILITY OF HEPTAMINOL SUPPOSITORIES PART III: Chemical Stability of Heptaminol Suppositories', Bulletin of Pharmaceutical Sciences Assiut University, 7(2), pp. 288-294. doi: 10.21608/bfsa.1984.89702
VANCOUVER
Kassem, A., El-Miligi, M., Ali, S. FORMULATION AND STABILITY OF HEPTAMINOL SUPPOSITORIES PART III: Chemical Stability of Heptaminol Suppositories. Bulletin of Pharmaceutical Sciences Assiut University, 1984; 7(2): 288-294. doi: 10.21608/bfsa.1984.89702
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