SYNTHESIS AND ANTICONVULSANT ACTIVITY OF 1,3-DISUBSTITUTED 2,4(1H,3H)QUINAZOLINEDIONE

Document Type : Original Article

Author

Pharmaceutical Chemistry Department, Faculty of Pharmacy, Al-Azhar University, Cairo, Egypt

Abstract

Some new 2,4(1H,3H)-quinazolinedione were synthesized and characterized by elemental analysis, IR, 1HNMR and Ms spectral data. Pharmacological evaluation of some of the synthesized compounds as anticonvulsants showed that they displayed weak anticonvulsant activity relative to phenobarbitone sodium as reference drug.